How brain state and context reshape communication across the visual hierarchy
Summary
We study the brain as a network whose effective connections change with sensory input, behavioral state, and the internal dynamics already in motion. Our work shows that stimulus type reshapes functional-network topology and that the balance among stimulus drive, behavior, and internal dynamics changes across brain states and the visual hierarchy. In our new bioRxiv preprint, Structured Sparsification of Signal-Transmission Networks Enhances Visual Information Coding, we find that locomotion is associated with fewer, more local, modular, feature-specific, and feedforward interactions, together with faster and more faithful sensory coding; rate-based models link these improvements to reduced shared variability and more feedforward signal transmission. We now ask which functional connections remain stable across states, how arousal and behavior select different communication pathways, and how feedforward, recurrent, and cross-area interactions balance coding speed with robustness.
From the lab
Related publications from our group
Structured Sparsification of Signal-Transmission Networks Enhances Visual Information Coding
Links state-dependent structured sparsification of cortical signal-transmission networks to faster and more faithful visual coding.
Deciphering neuronal variability across states reveals dynamic sensory encoding
Separates stimulus, behavioral, and internal contributions to neural variability across states and areas.
Stimulus type shapes the topology of cellular functional networks in mouse visual cortex
Shows that functional-network organization depends on the sensory ensemble being processed.
Multi-regional module-based signal transmission in mouse visual cortex
Describes modular routes for feedforward and recurrent signal transmission.